Systems Biology - (Lecture Notes on Mathematical Modelling in the Life Sciences) by Jinzhi Lei (Paperback)
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<p/><br></br><p><b> Book Synopsis </b></p></br></br><p>This book discusses the mathematical simulation of biological systems, with a focus on the modeling of gene expression, gene regulatory networks and stem cell regeneration. The diffusion of morphogens is addressed by introducing various reaction-diffusion equations based on different hypotheses concerning the process of morphogen gradient formation. The robustness of steady-state gradients is also covered through boundary value problems. </p><p>The introduction gives an overview of the relevant biological concepts (cells, DNA, organism development) and provides the requisite mathematical preliminaries on continuous dynamics and stochastic modeling. A basic understanding of calculus is assumed.</p><p> </p><p>The techniques described in this book encompass a wide range of mechanisms, from molecular behavior to population dynamics, and the inclusion of recent developments in the literature together with first-hand results make it an ideal reference for both new students and experienced researchers in the field of systems biology and applied mathematics.</p><p/><br></br><p><b> From the Back Cover </b></p></br></br><p></p><p>This book discusses the mathematical simulation of biological systems, with a focus on the modeling of gene expression, gene regulatory networks and stem cell regeneration. The diffusion of morphogens is addressed by introducing various reaction-diffusion equations based on different hypotheses concerning the process of morphogen gradient formation. The robustness of steady-state gradients is also covered through boundary value problems. </p> <p>The introduction gives an overview of the relevant biological concepts (cells, DNA, organism development) and provides the requisite mathematical preliminaries on continuous dynamics and stochastic modeling. A basic understanding of calculus is assumed.</p> <p>The techniques described in this book encompass a wide range of mechanisms, from molecular behavior to population dynamics, and the inclusion of recent developments in the literature together with first-hand results make it an ideal reference for both new students and experienced researchers in the field of systems biology and applied mathematics.</p><br><p></p><p/><br></br><p><b> About the Author </b></p></br></br>Jinzhi Lei (Ph.D. 2001, Beihang University) is Professor at the School of Mathematical Sciences, Tiangong University, China. He was a postdoc at UC, Irvine (2004-2005) and Associate Researcher at the Zhou Pei-Yuan Center for Applied Mathematics, Tsinghua University, China (2006-2019). His research focuses on modeling dynamical blood diseases, cancer development and stem cell regeneration.
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