HPLC and Uhplc for Practicing Scientists - 2nd Edition by Michael W Dong (Paperback)
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<p/><br></br><p><b> About the Book </b></p></br></br>"Many things have changed in HPLC in the last ten years since the publication of the first edition. First and foremost is the advent of UHPLC (ultra-high-pressure liquid chromatography) and the conttinuing migration of HPLC to UHPLC, the modern standard platform. Since UHPLC is an improved and higher-performance HPLC platform based on the same chromatographic theories. they share many commonalities such as columns and instrument modules. The 2nd edition, therefore, includes a substantial overview of all the fundamentals and practice of HPLC to include updates on UHPLC. There are three new chapters: UHPLC (standalone chapter on concepts, benefits, practice, and limitations), LC/MS, and the analysis of recombinant biologics particularly monoclonal antibodies (mAbs) used as therapeutics. While all chapters are revised in the new edition, five chapters are mostly rewritten including HPLC columns, instrumentation, pharmaceutical analysis, method development, and regulatory aspects"--<p/><br></br><p><b> Book Synopsis </b></p></br></br><p><b>A concise yet comprehensive reference guide on HPLC/UHPLC that focuses on its fundamentals, latest developments, and best practices in the pharmaceutical and biotechnology industries</b></p> <p>Written <i>for</i> practitioners <i>by</i> an expert practitioner, this new edition of <i>HPLC and UHPLC for Practicing Scientists</i> adds numerous updates to its coverage of high-performance liquid chromatography, including comprehensive information on UHPLC (ultra-high-pressure liquid chromatography) and the continuing migration of HPLC to UHPLC, the modern standard platform. In addition to introducing readers to HPLC's fundamentals, applications, and developments, the book describes basic theory and terminology for the novice, and reviews relevant concepts, best practices, and modern trends for the experienced practitioner. </p> <p><i>HPLC and UHPLC for Practicing Scientists, Second Edition</i> offers three new chapters. One is a standalone chapter on UHPLC, covering concepts, benefits, practices, and potential issues. Another examines liquid chromatography/mass spectrometry (LC/MS). The third reviews at the analysis of recombinant biologics, particularly monoclonal antibodies (mAbs), used as therapeutics. While all chapters are revised in the new edition, five chapters are essentially rewritten (HPLC columns, instrumentation, pharmaceutical analysis, method development, and regulatory aspects). The book also includes problem and answer sections at the end of each chapter. </p> <ul> <li>Overviews fundamentals of HPLC to UHPLC, including theories, columns, and instruments with an abundance of tables, figures, and key references</li> <li>Features brand new chapters on UHPLC, LC/MS, and analysis of recombinant biologics</li> <li>Presents updated information on the best practices in method development, validation, operation, troubleshooting, and maintaining regulatory compliance for both HPLC and UHPLC</li> <li>Contains major revisions to all chapters of the first edition and substantial rewrites of chapters on HPLC columns, instrumentation, pharmaceutical analysis, method development, and regulatory aspects</li> <li>Includes end-of-chapter quizzes as assessment and learning aids</li> <li>Offers a reference guide to graduate students and practicing scientists in pharmaceutical, biotechnology, and other industries</li> </ul> <p>Filled with intuitive explanations, case studies, and clear figures, <i>HPLC and UHPLC for Practicing Scientists, Second Edition</i> is an essential resource for practitioners of all levels who need to understand and utilize this versatile analytical technology. It will be a great benefit to every busy laboratory analyst and researcher.</p><p/><br></br><p><b> From the Back Cover </b></p></br></br><p><b>A concise yet comprehensive reference guide on HPLC/UHPLC that focuses on its fundamentals, latest developments, and best practices in the pharmaceutical and biotechnology industries</b> <p>Written <i>for</i> practitioners by an expert practitioner, this new edition of <i>HPLC and UHPLC for Practicing Scientists</i> adds numerous updates to its coverage of high-performance liquid chromatography, including comprehensive information on UHPLC (ultra-high-pressure liquid chromatography) and the continuing migration of HPLC to UHPLC, the modern standard platform. In addition to introducing readers to HPLC's fundamentals, applications, and developments, the book describes basic theory and terminology for the novice, and reviews relevant concepts, best practices, and modern trends for the experienced practitioner. <p><i>HPLC and UHPLC for Practicing Scientists, Second Edition</i> offers three new chapters. One is a standalone chapter on UHPLC, covering concepts, benefits, practices, and potential issues. Another examines liquid chromatography/mass spectrometry (LC/MS). The third reviews at the analysis of recombinant biologics, particularly monoclonal antibodies (mAbs), used as therapeutics. While all chapters are revised in the new edition, five chapters are essentially rewritten (HPLC columns, instrumentation, pharmaceutical analysis, method development, and regulatory aspects). The book also includes problem and answer sections at the end of each chapter. <ul> <li>Overviews fundamentals of HPLC to UHPLC, including theories, columns, and instruments with an abundance of tables, figures, and key references</li> <li>Features brand new chapters on UHPLC, LC/MS, and analysis of recombinant biologics</li> <li>Presents updated information on the best practices in method development, validation, operation, troubleshooting, and maintaining regulatory compliance for both HPLC and UHPLC systems</li> <li>Contains major revisions to all chapters of the first edition and substantial rewrites of chapters on HPLC columns, instrumentation, pharmaceutical analysis, method development, and regulatory aspects</li> <li>Includes end-of-chapter quizzes as assessment and learning aids</li> <li>Offers a reference guide to graduate students and practicing scientists in pharmaceutical, biotechnology, and other industries</li> </ul> <p>Filled with intuitive explanations, case studies, and clear figures, <i>HPLC and UHPLC for Practicing Scientists, Second Edition</i> is an essential resource for practitioners of all levels who need to understand and utilize this versatile analytical technology. It will be a great benefit to every busy laboratory analyst and researcher.<p/><br></br><p><b> About the Author </b></p></br></br><p><b>MICHAEL W. DONG, PHD, </b> is the Principal of MWD Consulting, providing expert training and consulting service in HPLC/UHPLC, and pharmaceutical analysis. He is a former senior scientist, for GENENTECH, INC, small molecule analytical chemistry and quality control department. Dr. Dong conducts short courses on HPLC/UHPLC, drug development process, and drug quality at national meetings such as Pittcon, ACS, HPLC, and EAS. He also provides consulting services on CMC, HPLC method development, and solving drug quality issues. He holds a Ph.D. degree in analytical chemistry and has authored 120+ journal articles and three books.
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