Cytotoxic Payloads for Antibody-Drug Conjugates - (ISSN) (Hardcover)
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<p/><br></br><p><b> About the Book </b></p></br></br><p>Antibody-drug conjugates are a promising areas of anticancer drug discovery, conveying several advantages, including the ability to select likely responders, efficient delivery of cytotoxic agents and reduced toxicity. This book describes payloads used to date and novel payloads that may be used clinically in the future.</p><p/><br></br><p><b> Book Synopsis </b></p></br></br>The antibody-drug conjugates (ADCs) field is one of the fastest growing areas of drug discovery and represents a large body of research. ADCs deliver a cytotoxic payload, a key component of the overall ADC design, specifically to cancer cells by attaching it to an antibody targeted to antigens on the cell surface. This book discusses the range of payloads used to date along with their advantages and disadvantages, and describes novel payloads at the research stage that may be used clinically in the near future.<p/><br></br><p><b> Review Quotes </b></p></br></br><br>Plan on having this sitting on your desk shelf as the definitive guide to ADC payloads for the next 5-10 years.--Justin Sweeley, Novasep "5 Things You Need To Know This Week About ADCs - July 27, 2019 ADCReview "<br>
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