Protein Crystallography - (Methods in Molecular Biology) by Alexander Wlodawer & Zbigniew Dauter & Mariusz Jaskolski (Hardcover)
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<p/><br></br><p><b> Book Synopsis </b></p></br></br><p>1. Expression and Purification of Recombinant Proteins in Escherichia Coli with a His<sub>6</sub> or Dual His<sub>6</sub>-MBP Tag</p> <p>Sreejith Raran-Kurussi and David S. Waugh</p> <p> </p> <p>2. Protein Crystallization</p> <p>Alexander McPherson </p> <p> </p> <p>3. Advanced Methods of Protein Crystallization</p> <p>Abel Moreno</p> <p> </p> <p>4. The 'Sticky Patch' Model of Crystallization and Modification of Proteins for Enhanced Crystallizability</p> <p>Zygmunt S. Derewenda and Adam Godzik</p> <p> </p> <p>5. Crystallization of Membrane Proteins: and Overview</p> <p>Andrii Ishchenko, Enrique Abola, and Vadim Cherezov</p> <p> </p> <p>6. Locating and Visualizing Crystals for X-ray Diffraction Experiments</p> <p>Michael Becker, David J. Kissick, and Craig M. Ogata</p> <p> </p> <p>7. Collection of X-ray Diffraction Data from Macromolecular Crystals</p> <p>Zbigniew Dauter</p> <p> </p> <p>8. Identifying and Overcoming Crystal Pathologies: Disorder and Twinning</p> <p> Michael C. Thompson</p> <p> </p> <p>9. Applications of X-ray Micro-beam for Data Collection</p> Ruslan Sanishvili and Robert F. Fischetti<p></p> <p> </p> <p>10. Serial Synchrotron X-ray Crystallography (SSX)</p> <p>Kay Diederichs and Meitian Wang</p> <p><br></p> <p>11. Time-Resolved Macromolecular Crystallography at Modern X-ray Sources</p> <p>Marius Schmidt</p> <p> </p> <p>12. Structure Determination Using X-ray Free-electron Laser Pulses</p> <p>Henry N. Chapman</p> <p> </p> <p>13. Processing of XFEL Data</p> <p>Thomas A. White</p> <p></p> <p>14. Many Ways to Derivatize Macromolecules and their Crystals for Phasing</p> <p>Miroslawa Dauter and Zbigniew Dauter</p> <p>15. Experimental Phasing: Substructure Solution and Density Modification as Implemented in SHELX</p> Andrea Thorn<p></p> <p> </p> <p>16. Contemporary Use of Anomalous Diffraction in Biomolecular Structure Analysis</p> <p>Qun Liu and Wayne A. Hendrickson</p> <p></p> <p>17. Long-Wavelength X-ray Diffraction and its Applications in Macromolecular Crystallography</p> <p>Manfred S. Weiss</p> <p> </p> <p>18. Acknowledging Errors: Advanced Molecular Replacement with Phaser</p> <p> Airlie J. McCoy</p> <p> </p> <p>19. Rosetta Structure Prediction as a Tool for Solving Difficult Molecular Replacement Problems</p> <p>Frank DiMaio</p> <p> </p> <p>20. Radiation Damage in Macromolecular Crystallography</p> <p>Elspeth F. Garman and Martin Weik</p> <p> </p> 21. Boxes of Model Building and Visualization<p></p> <p>Dusan Turk</p> <p> </p> <p>22. Structure Refinement at Atomic Resolution</p> <p>Mariusz Jaskolski</p> <p> </p> <p>23. Low Resolution Refinement of Atomic Models against Crystallographic Data</p> <p>Robert A. Nicholls, Oleg Kovalevskiy, and Garib N. Murshudov</p> <p> </p> <p>24. Stereochemistry and Validation of Macromolecular Structures</p> <p>Alexander Wlodawer</p> <p> </p> <p>25. Validation of Protein-Ligand Crystal Structure Models: Small Molecule and Peptide Ligands</p> <p>Edwin Pozharski, Marc C. Deller and Bernhard Rupp</p> <p> </p> <p>26. Protein Data Bank - the Single Global Macromolecular Structure Archive Managed by the Worldwide Protein Data Bank</p> <p>Stephen K. Burley Helen M. Berman, Gerard J. Kleywegt, John L. Markley, Haruki Nakamura, and Sameer Velankar</p> <p> </p> <p>27. Databases, Repositories and Other Data Resources in Structural Biology</p> <p>Heping Zheng, Przemyslaw J. Porebski, Marek Grabowski, David R. Cooper, and Wladek Minor</p> <p><br></p><p/><br></br><p><b> From the Back Cover </b></p></br></br>This volume provides methods for modern macromolecular crystallography, including all steps leading to crystal structure determination and analysis. Written in the highly successful <i>Methods in Molecular Biology </i>series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. <p>Authoritative and practical, <i>Protein Crystallography</i> aims to ensure successful results in the further study of this vital field.</p>
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