Fred & Marjorie - by Deborah Kerbel (Hardcover)
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<p/><br></br><p><b> About the Book </b></p></br></br>"One hundred years ago, juvenile diabetes was a death sentence for millions of people around the world, most of them children. FRED & MARJORIE tells the story the discovery of insulin, a treatment for this disease and one of the most impactful milestones in medical science. Frederick Banting was a young doctor who was haunted by the memories of the diabetic children he'd treated at Toronto's Hospital for Sick Children. One night, though, he was struck by inspiration--would it be possible to isolate the mysterious secretions of the pancreas (what we now call insulin) and use this substance to treat diabetes? In May 1921, the University of Toronto gave Banting a small lab and a student assistant, Charles Best, to work through Banting's hypothesis. Their test subjects were street dogs--a fact that pained Banting, who had a deep fondness for animals. Banting and Best took exceptional care of the dogs, and Banting ended up giving one the dogs a name -- Marjorie. And when Marjorie--whose pancreas had been replaced by insulin injections--lived 70 days, the experiment was deemed a success. The next step was to try the treatment on a dying child. The effects of insulin on the first human diabetic patient were deemed practically miraculous. However, many dogs did die for this to happen, including Marjorie, whom Banting described as "the most important dog in the world." The back matter includes an Author's Note that provides more information about the disease, as well as about Banting, Best and the insulin dogs. Another section addresses the ethical dilemma of using animals in medical research."--<p/><br></br><p><b> Book Synopsis </b></p></br></br><b>A graphic novel for ages 8 to 12 that tells the true story of the life-saving discovery of insulin</b><b><br></b><br>"Readers will want to dig deeper into this true story of canine heroes and lifesaving science." -- <em>Kirkus Reviews</em> <p/><em><br></em><br>In 1921, Frederick Banting was a young doctor with an idea: could the mysterious secretions of the pancreas be used to treat diabetes? We now call this substance insulin, and its life-saving discovery was an impactful milestone in medical science. <p/><br>Banting and his assistant, Charles Best, worked together in a small lab to test the theory with street dogs. Banting formed a special bond with one of his test dogs and gave her a name: Marjorie. After Marjorie responded well to insulin treatments, the treatments went on to be used for humans with diabetes--and the results were deemed practically miraculous. <p/><br>A real-life scientific milestone told in an innovative graphic novel format, the book also thoughtfully discusses the use of animals for medical research, including back matter on the subject and further information about diabetes.<br><p/><br></br><p><b> Review Quotes </b></p></br></br><br>"Chronicles a medical breakthrough that has saved the lives of millions of children ... A laudably frank, sensitive account."-- "School Library Journal - STARRED REVIEW"<br><br>"This book is a great introduction to a topic that many readers might not be aware of ... A great addition."-- "School Library Connection"<br><br>"A remarkably fascinating and poignant story ... A great STEM book."-- "The Picture Book Buzz"<br><br>Readers will want to dig deeper into this true story of canine heroes and lifesaving science.-- "Kirkus Reviews"<br><br>In both the writing and artwork, this is a story effectively told in an attractive and accessible way.-- "Booklist"<br>
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